BARD1

Gene Symbol:
BARD1
HGNC:952
Locus Group:
protein-coding gene
Locus Type:
gene with protein product
Location:
2q35
Filters:

Definitive classifications

AD
11/30/2022
Evaluated
07/02/2025
Submitted
BARD1-related cancer predisposition
AD
09/03/2024
Evaluated
12/05/2025
Submitted
ClinGen
Evidence:

BARD1 was discovered as a binding partner to BRCA1 in 1996 (Wu et al., PMID: 8944023) and was fir... Read more

Strong classifications

hereditary breast carcinoma
Submitted as: OMIM:114480
AD
11/01/2023
Evaluated
01/02/2024
Submitted
hereditary breast carcinoma
Submitted as: OMIM:114480
AD
03/08/2021
Evaluated
11/30/2023
Submitted

Disputed Evidence classifications

familial ovarian cancer
AD
08/29/2024
Evaluated
12/05/2025
Submitted
ClinGen
Evidence:

BARD1 was first reported in relation to Ovarian Cancer in 1998 (Thai et al., PMID: 9425226). BARD... Read more

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