Gene Symbol:
MSH6
HGNC:7329
Locus Group:
protein-coding gene
Locus Type:
gene with protein product
Location:
2p16.3
Filters:

Breast cancer classifications

AD
07/14/2022
Evaluated
08/19/2023
Submitted

Endometrial cancer classifications

endometrial cancer
Submitted as: OMIM:608089
AD
11/29/2016
Evaluated
09/11/2023
Submitted

Hereditary breast carcinoma classifications

hereditary breast carcinoma
AD
07/26/2017
Evaluated
10/18/2023
Submitted

Lynch syndrome classifications

Lynch syndrome
Submitted as: Orphanet:144
AD
09/14/2021
Evaluated
09/14/2021
Submitted

Lynch syndrome 5 classifications

Lynch syndrome 5
Submitted as: OMIM:614350
AD
03/04/2020
Evaluated
03/31/2021
Submitted
Lynch syndrome 5
Submitted as: OMIM:614350
AD
04/07/2020
Evaluated
04/01/2021
Submitted
Laboratory for Molecular Medicine
Evidence: This gene-disease relationship has undergone rapid assessment. Classifications are based on prelimin... Read more
Lynch syndrome 5
Submitted as: OMIM:614350
AD
10/13/2023
Evaluated
11/30/2023
Submitted

Malignant pancreatic neoplasm classifications

malignant pancreatic neoplasm
AD
03/04/2020
Evaluated
03/31/2021
Submitted

Mismatch repair cancer syndrome 1 classifications

mismatch repair cancer syndrome 1
Submitted as: Orphanet:252202
AR
09/14/2021
Evaluated
09/14/2021
Submitted
mismatch repair cancer syndrome 1
AR
10/09/2018
Evaluated
10/18/2023
Submitted
mismatch repair cancer syndrome 1
Submitted as: OMIM:276300
AR
11/29/2016
Evaluated
09/11/2023
Submitted

Mismatch repair cancer syndrome 3 classifications

mismatch repair cancer syndrome 3
Submitted as: OMIM:619097
AR
04/07/2020
Evaluated
04/01/2021
Submitted
Laboratory for Molecular Medicine
Evidence: This gene-disease relationship has undergone rapid assessment. Classifications are based on prelimin... Read more
mismatch repair cancer syndrome 3
Submitted as: OMIM:619097
AR
02/02/2023
Evaluated
11/30/2023
Submitted

Muir-Torre syndrome classifications

Muir-Torre syndrome
AD
10/15/2020
Evaluated
03/31/2021
Submitted
Muir-Torre syndrome
Submitted as: Orphanet:587
AD
09/14/2021
Evaluated
09/14/2021
Submitted

Ovarian cancer classifications

AD
10/27/2020
Evaluated
03/31/2021
Submitted

Prostate cancer classifications

AD
07/14/2022
Evaluated
08/19/2023
Submitted

Rhabdomyosarcoma classifications

AR
02/11/2021
Evaluated
03/31/2021
Submitted

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The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. The GenCC does not independently verify the submitted information. Though the information is obtained from sources believed to be reliable, no warranty, expressed or implied, is made regarding accuracy, adequacy, completeness, reliability or usefulness of any information. This disclaimer applies to both isolated and aggregate uses of the information. The information is provided on an "as is" basis, collected through periodic submission and therefore may not represent the most up-to-date information from the submitters. If you have questions about the medical relevance of information contained on this website, please see a healthcare professional; if you have questions about specific gene-disease claims, please contact the relevant sources; and if you have questions about the representation of the data on this website, please contact gencc@thegencc.org.