Gene Symbol:
APC
HGNC:583
Locus Group:
protein-coding gene
Locus Type:
gene with protein product
Location:
5q22.2
Filters:

Definitive classifications

familial adenomatous polyposis 1
Submitted as: OMIM:175100
AD
08/30/2018
Evaluated
12/24/2020
Submitted
desmoid tumor
Submitted as: OMIM:135290
AD
09/01/2017
Evaluated
09/11/2023
Submitted
gastric adenocarcinoma and proximal polyposis of the stomach
AD
06/20/2022
Evaluated
04/21/2024
Submitted
classic or attenuated familial adenomatous polyposis
AD
06/20/2022
Evaluated
04/21/2024
Submitted

Strong classifications

desmoid tumor
Submitted as: OMIM:135290
AD
03/04/2020
Evaluated
03/31/2021
Submitted
familial adenomatous polyposis 1
Submitted as: OMIM:175100
AD
03/04/2020
Evaluated
03/31/2021
Submitted
familial adenomatous polyposis 1
Submitted as: OMIM:175100
AD
03/08/2023
Evaluated
11/30/2023
Submitted
gastric adenocarcinoma and proximal polyposis of the stomach
Submitted as: OMIM:619182
AD
04/16/2021
Evaluated
11/30/2023
Submitted

Moderate classifications

familial adenomatous polyposis 1
Submitted as: OMIM:175100
AD
02/11/2021
Evaluated
03/31/2021
Submitted

Supportive classifications

Cenani-Lenz syndactyly syndrome
Submitted as: Orphanet:3258
AR
09/14/2021
Evaluated
09/14/2021
Submitted
Turcot syndrome with polyposis
Submitted as: Orphanet:99818
AD
09/14/2021
Evaluated
09/14/2021
Submitted
APC-related attenuated familial adenomatous polyposis
Submitted as: Orphanet:247806
AD
09/14/2021
Evaluated
09/14/2021
Submitted
gastric adenocarcinoma and proximal polyposis of the stomach
Submitted as: Orphanet:314022
AD
09/14/2021
Evaluated
09/14/2021
Submitted

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