Gene Symbol:
SCN1B
HGNC:10586
Locus Group:
protein-coding gene
Locus Type:
gene with protein product
Location:
19q13.11
Filters:

Definitive classifications

generalized epilepsy with febrile seizures plus, type 1
Submitted as: OMIM:604233
AD
07/22/2015
Evaluated
11/25/2020
Submitted
Brugada syndrome 5
Submitted as: OMIM:612838
AD
07/22/2015
Evaluated
09/11/2023
Submitted
generalized epilepsy with febrile seizures plus
AD
12/13/2022
Evaluated
10/18/2023
Submitted
developmental and epileptic encephalopathy
AR
01/04/2022
Evaluated
10/18/2023
Submitted

Strong classifications

developmental and epileptic encephalopathy, 52
Submitted as: OMIM:617350
AR
04/29/2021
Evaluated
11/30/2023
Submitted
generalized epilepsy with febrile seizures plus, type 1
Submitted as: OMIM:604233
AD
04/09/2020
Evaluated
11/30/2023
Submitted

Moderate classifications

Brugada syndrome 5
Submitted as: OMIM:612838
AD
08/20/2020
Evaluated
03/31/2021
Submitted
generalized epilepsy with febrile seizures plus, type 1
AD
02/17/2021
Evaluated
10/27/2022
Submitted

Supportive classifications

developmental and epileptic encephalopathy
Submitted as: Orphanet:1934
AD
09/14/2021
Evaluated
09/14/2021
Submitted
progressive familial heart block
Submitted as: Orphanet:871
AD
09/14/2021
Evaluated
09/14/2021
Submitted
Dravet syndrome
Submitted as: Orphanet:33069
AD
09/14/2021
Evaluated
09/14/2021
Submitted
generalized epilepsy with febrile seizures plus
Submitted as: Orphanet:36387
AD
09/14/2021
Evaluated
09/14/2021
Submitted

Limited classifications

Brugada syndrome 5
Submitted as: OMIM:612838
AR
03/02/2021
Evaluated
03/31/2021
Submitted
atrial fibrillation, familial, 13
Submitted as: OMIM:615377
Unknown
07/31/2017
Evaluated
11/30/2023
Submitted
Brugada syndrome 5
Submitted as: OMIM:612838
AD
08/20/2021
Evaluated
11/30/2023
Submitted

Disputed Evidence classifications

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